Product Data Sheet
AMPK activator 4
Catalog No. A57649
AMPK Activator 4 is a selective activator of AMP-activated protein kinase (AMPK) that does not inhibit mitochondrial complex I. This compound enhances AMPK activity specifically in muscle tissues, demonstrating a dose-dependent improvement in glucose tolerance in normal mice. Furthermore, it significantly reduces fasting blood glucose levels and ameliorates insulin resistance in db/db diabetic mice, showcasing its potential as an anti-hyperglycemic agent for diabetes research.
Chemical Information
| Catalog Num | A57649 |
|---|---|
| M. Wt | 420.89 |
| Formula | C24H21ClN2O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2493239-46-4 |
| Synonyms | |
| SMILES | CC(C)(OC1=CC=C(Cl)C=C1)C(NC2=CC=C(OCC3=CC=C(C#N)C=C3)C=C2)=O |
Biological Activity
| Description | AMPK Activator 4 is a selective activator of AMP-activated protein kinase (AMPK) that does not inhibit mitochondrial complex I. This compound enhances AMPK activity specifically in muscle tissues, demonstrating a dose-dependent improvement in glucose tolerance in normal mice. Furthermore, it significantly reduces fasting blood glucose levels and ameliorates insulin resistance in db/db diabetic mice, showcasing its potential as an anti-hyperglycemic agent for diabetes research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
