Product Data Sheet
AMPK-IN-1
Catalog No. A57653
AMPK-IN-1 is a potent activator of AMP-activated protein kinase (AMPK), specifically targeting the α2β2γ1 isoform with an EC50 of 551 nM. This compound facilitates the phosphorylation of eEF2 through a mechanism that is independent of mTORC1 signaling. AMPK-IN-1 is valuable for research into metabolic regulation and the cellular energy response, offering insights into the therapeutic potential for conditions related to energy imbalances.
Chemical Information
| Catalog Num | A57653 |
|---|---|
| M. Wt | 431.87 |
| Formula | C24H18ClN3O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1219739-95-3 |
| Synonyms | |
| SMILES | O=C(O)C1=CC(OC2=NC3=CC(Cl)=C(C4=CC5=C(C=C4)C=CN5C)C=C3N2)=CC=C1C |
Biological Activity
| Description | AMPK-IN-1 is a potent activator of AMP-activated protein kinase (AMPK), specifically targeting the α2β2γ1 isoform with an EC50 of 551 nM. This compound facilitates the phosphorylation of eEF2 through a mechanism that is independent of mTORC1 signaling. AMPK-IN-1 is valuable for research into metabolic regulation and the cellular energy response, offering insights into the therapeutic potential for conditions related to energy imbalances. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
