Product Data Sheet
AMPK activator 8
Catalog No. A57662
AMPK activator 8 is a potent activator of AMP-activated protein kinase (AMPK), demonstrating EC50 values of 11, 27, 4, 2, and 4 nM for various AMPK isoforms: rAMPK α1β1γ1, rAMPK α2β1γ1, rAMPK α1β2γ1, rAMPK α2β2γ1, and rAMPK α2β2γ3. This compound is particularly valuable for studying metabolic disorders, specifically type 2 diabetes, by enhancing AMPK activity and modulating glucose metabolism. Its high specificity and efficacy make it an important tool for researchers exploring AMPK-related pathways and therapeutic interventions.
Chemical Information
| Catalog Num | A57662 |
|---|---|
| M. Wt | 480.90 |
| Formula | C25H21ClN2O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1852451-96-7 |
| Synonyms | |
| SMILES | ClC1=C(C2=CC=C(C3=C(C=CC=C3O)O)C=C2)C=C4NC(O[C@H]5[C@]6([H])[C@]([C@@H](CO6)O)([H])OC5)=NC4=C1 |
Biological Activity
| Description | AMPK activator 8 is a potent activator of AMP-activated protein kinase (AMPK), demonstrating EC50 values of 11, 27, 4, 2, and 4 nM for various AMPK isoforms: rAMPK α1β1γ1, rAMPK α2β1γ1, rAMPK α1β2γ1, rAMPK α2β2γ1, and rAMPK α2β2γ3. This compound is particularly valuable for studying metabolic disorders, specifically type 2 diabetes, by enhancing AMPK activity and modulating glucose metabolism. Its high specificity and efficacy make it an important tool for researchers exploring AMPK-related pathways and therapeutic interventions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
