Product Data Sheet

BI-9774

Catalog No. A57671

main product photo
BI-9774 is a potent activator of 5' AMP-activated protein kinase (AMPK), with an IC50 ranging from 12 to 88 nM. This compound is primarily utilized in research focused on metabolic disorders, such as type 2 diabetes and obesity, as well as in cardiovascular disease studies, including myocardial ischemia and heart failure. Its ability to modulate AMPK activity makes it a valuable tool for investigating therapeutic strategies in these areas.
Chemical Information
Catalog NumA57671
M. Wt541.02
FormulaC26H25ClN4O5S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1644498-53-2
Synonyms
SMILESO(C1=NC=2C(N1)=CC(Cl)=C(N2)C3=CC=C(C=C3)C4=CC=C(N=S(C)(C)=O)C=C4)[C@H]5[C@@]6([C@](OC5)([C@H](O)CO6)[H])[H]
Biological Activity
DescriptionBI-9774 is a potent activator of 5' AMP-activated protein kinase (AMPK), with an IC50 ranging from 12 to 88 nM. This compound is primarily utilized in research focused on metabolic disorders, such as type 2 diabetes and obesity, as well as in cardiovascular disease studies, including myocardial ischemia and heart failure. Its ability to modulate AMPK activity makes it a valuable tool for investigating therapeutic strategies in these areas.
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SHIPPING AND STORAGE
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