Product Data Sheet
METTL1-WDR4-IN-2
Catalog No. A57695
METTL1-WDR4-IN-2 is a selective inhibitor of the METTL1-WDR4 methyltransferase complex, exhibiting an IC50 value of 41 μM. This compound demonstrates significant selectivity, with IC50 values of 958 μM against METTL3-14 and 208 μM against METTL16. METTL1-WDR4-IN-2 is valuable for investigating the role of RNA methylation in cancer and other biological processes related to epitranscriptomics.
Chemical Information
| Catalog Num | A57695 |
|---|---|
| M. Wt | 509.53 |
| Formula | C24H23N5O6S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2919742-07-5 |
| Synonyms | |
| SMILES | O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=CN=C3N)O[C@@H]1CSCC4=CC(C(O)=O)=CC(C5=CC=C(O)C=C5)=C4 |
Biological Activity
| Description | METTL1-WDR4-IN-2 is a selective inhibitor of the METTL1-WDR4 methyltransferase complex, exhibiting an IC50 value of 41 μM. This compound demonstrates significant selectivity, with IC50 values of 958 μM against METTL3-14 and 208 μM against METTL16. METTL1-WDR4-IN-2 is valuable for investigating the role of RNA methylation in cancer and other biological processes related to epitranscriptomics. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
