Product Data Sheet
(R)-GSK-3685032
Catalog No. A57696
(R)-GSK-3685032 is a reversible inhibitor selectively targeting DNMT1, exhibiting a non-time-dependent and noncovalent mechanism of action. With an IC50 value of 0.036 μM, it effectively induces significant loss of DNA methylation and promotes transcriptional activation. This compound is suitable for research applications exploring epigenetic modifications in cancer biology, particularly in studies focused on cancer cell growth inhibition.
Chemical Information
| Catalog Num | A57696 |
|---|---|
| M. Wt | 420.53 |
| Formula | C22H24N6OS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2170140-50-6 |
| Synonyms | |
| SMILES | N#CC1=C(N2CCC(CC2)N)N=C(C(C#N)=C1CC)S[C@H](C3=CC=CC=C3)C(N)=O |
Biological Activity
| Description | (R)-GSK-3685032 is a reversible inhibitor selectively targeting DNMT1, exhibiting a non-time-dependent and noncovalent mechanism of action. With an IC50 value of 0.036 μM, it effectively induces significant loss of DNA methylation and promotes transcriptional activation. This compound is suitable for research applications exploring epigenetic modifications in cancer biology, particularly in studies focused on cancer cell growth inhibition. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
