Product Data Sheet
DC_517
Catalog No. A57698
DC_517 is a selective inhibitor of DNA methyltransferase 1 (DNMT1), exhibiting an IC50 of 1.7 μM and a Kd of 0.91 μM. This compound effectively modulates DNA methylation patterns, making it a valuable tool for studies related to epigenetic regulation, gene expression, and cancer research. Research applications include exploring the roles of DNMT1 in cellular processes and evaluating potential therapeutic strategies for diseases associated with abnormal DNA methylation.
Chemical Information
| Catalog Num | A57698 |
|---|---|
| M. Wt | 505.65 |
| Formula | C33H35N3O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 500017-70-9 |
| Synonyms | |
| SMILES | OC(CNC(C)C)COC(CN1C(C=CC=C2)=C2C3=C1C=CC=C3)CN(C4=CC=CC=C45)C6=C5C=CC=C6 |
Biological Activity
| Description | DC_517 is a selective inhibitor of DNA methyltransferase 1 (DNMT1), exhibiting an IC50 of 1.7 μM and a Kd of 0.91 μM. This compound effectively modulates DNA methylation patterns, making it a valuable tool for studies related to epigenetic regulation, gene expression, and cancer research. Research applications include exploring the roles of DNMT1 in cellular processes and evaluating potential therapeutic strategies for diseases associated with abnormal DNA methylation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
