Product Data Sheet
Levetiracetam-d3
Catalog No. A57724
Levetiracetam-d3 is a deuterated form of Levetiracetam, primarily targeting the synaptic vesicle protein SV2A. This antiepileptic compound enhances the efficacy of Temozolomide by promoting apoptosis and inhibiting the proliferation of glioblastoma stem cells. Levetiracetam-d3 also modulates histone deacetylase (HDAC) levels, leading to the silencing of MGMT and thereby increasing the sensitivity of cancer cells to Temozolomide treatment. This reagent is valuable for chemical research applications related to cancer therapy and neuropharmacology.
Chemical Information
| Catalog Num | A57724 |
|---|---|
| M. Wt | 173.23 |
| Formula | C8H11D3N2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1217851-16-5 |
| Synonyms | UCB L059-d3 |
| SMILES | [C@@H](C(N)=O)(CC([2H])([2H])[2H])N1C(=O)CCC1 |
Biological Activity
| Description | Levetiracetam-d3 is a deuterated form of Levetiracetam, primarily targeting the synaptic vesicle protein SV2A. This antiepileptic compound enhances the efficacy of Temozolomide by promoting apoptosis and inhibiting the proliferation of glioblastoma stem cells. Levetiracetam-d3 also modulates histone deacetylase (HDAC) levels, leading to the silencing of MGMT and thereby increasing the sensitivity of cancer cells to Temozolomide treatment. This reagent is valuable for chemical research applications related to cancer therapy and neuropharmacology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
