Product Data Sheet

METTL3-IN-3

Catalog No. A57821

main product photo
METTL3-IN-3 is a selective inhibitor of the methyltransferase METTL3, which plays a critical role in RNA m6A methylation. This compound demonstrates significant inhibition of METTL3 activity, thereby impacting the regulation of gene expression and RNA metabolism. METTL3-IN-3 is valuable for research applications focusing on epitranscriptomics, RNA modifications, and their implications in various biological processes and diseases.
Chemical Information
Catalog NumA57821
M. Wt555.44
FormulaC26H28BrFN6O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2767003-71-2
Synonyms
SMILESO[C@H]1[C@@H](O)[C@H](N2C=C(Br)C3=C(N)N=CN=C32)C[C@@H]1C4=CC(N5)=C(C=C5CNCC6(C7)CC7(F)C6)C=C4
Biological Activity
DescriptionMETTL3-IN-3 is a selective inhibitor of the methyltransferase METTL3, which plays a critical role in RNA m6A methylation. This compound demonstrates significant inhibition of METTL3 activity, thereby impacting the regulation of gene expression and RNA metabolism. METTL3-IN-3 is valuable for research applications focusing on epitranscriptomics, RNA modifications, and their implications in various biological processes and diseases.
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