Product Data Sheet
MRS1220
Catalog No. A57877
MRS1220 is a highly potent and selective antagonist of the human A3 adenosine receptor (hA3AR), exhibiting a Ki value of 0.59 nM. This compound is of significant interest for research related to diseases of the central nervous system and has demonstrated the ability to reduce glioblastoma tumor size and inhibit angiogenesis in vivo. Its distinct action on the A3 receptor makes it a valuable tool for studying mechanisms associated with neuroprotection and tumor biology.
Chemical Information
| Catalog Num | A57877 |
|---|---|
| M. Wt | 403.82 |
| Formula | C21H14ClN5O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 183721-15-5 |
| Synonyms | |
| SMILES | O=C(NC1=NC2=C(C=C(Cl)C=C2)C3=NC(C4=CC=CO4)=NN13)CC5=CC=CC=C5 |
Biological Activity
| Description | MRS1220 is a highly potent and selective antagonist of the human A3 adenosine receptor (hA3AR), exhibiting a Ki value of 0.59 nM. This compound is of significant interest for research related to diseases of the central nervous system and has demonstrated the ability to reduce glioblastoma tumor size and inhibit angiogenesis in vivo. Its distinct action on the A3 receptor makes it a valuable tool for studying mechanisms associated with neuroprotection and tumor biology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
