Product Data Sheet
(E)-8-(3-Chlorostyryl)caffeine
Catalog No. A57885
(E)-8-(3-Chlorostyryl)caffeine is a selective antagonist of the adenosine A2A receptor, which plays a significant role in neuronal signaling. In addition to its primary action, this compound also inhibits monoamine oxidase B (MAO-B) with a Ki value of 70 nM through a mechanism independent of its effects on the A2A receptor. Due to its dual activity, (E)-8-(3-Chlorostyryl)caffeine is of particular interest in research related to Parkinson's disease and other neurological disorders.
Chemical Information
| Catalog Num | A57885 |
|---|---|
| M. Wt | 330.77 |
| Formula | C16H15ClN4O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 147700-11-6 |
| Synonyms | (E)-CSC |
| SMILES | CN1C2=C(N(C(N(C2=O)C)=O)C)N=C1/C=C/C3=CC(Cl)=CC=C3 |
Biological Activity
| Description | (E)-8-(3-Chlorostyryl)caffeine is a selective antagonist of the adenosine A2A receptor, which plays a significant role in neuronal signaling. In addition to its primary action, this compound also inhibits monoamine oxidase B (MAO-B) with a Ki value of 70 nM through a mechanism independent of its effects on the A2A receptor. Due to its dual activity, (E)-8-(3-Chlorostyryl)caffeine is of particular interest in research related to Parkinson's disease and other neurological disorders. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
