Product Data Sheet
GS-9667
Catalog No. A57898
GS-9667 is a selective partial agonist of the A1 adenosine receptor (A1AdoR). This N6-5'-substituted adenosine analog effectively reduces cyclic AMP levels and inhibits the release of nonesterified fatty acids from epididymal adipocytes, demonstrating IC50 values of 6 nM and 44 nM, respectively. Its ability to inhibit lipolysis suggests potential applications in research related to Type 2 diabetes (T2DM) and dyslipidemia by lowering free fatty acids (FFA).
Chemical Information
| Catalog Num | A57898 |
|---|---|
| M. Wt | 461.51 |
| Formula | C21H24FN5O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 618380-90-8 |
| Synonyms | CVT 3619 |
| SMILES | O[C@H]1[C@@H](O[C@@H]([C@H]1O)CSC2=C(C=CC=C2)F)N3C4=NC=NC(N[C@H]5[C@@H](CCC5)O)=C4N=C3 |
Biological Activity
| Description | GS-9667 is a selective partial agonist of the A1 adenosine receptor (A1AdoR). This N6-5'-substituted adenosine analog effectively reduces cyclic AMP levels and inhibits the release of nonesterified fatty acids from epididymal adipocytes, demonstrating IC50 values of 6 nM and 44 nM, respectively. Its ability to inhibit lipolysis suggests potential applications in research related to Type 2 diabetes (T2DM) and dyslipidemia by lowering free fatty acids (FFA). |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
