Product Data Sheet
2-Chloro-N-cyclopentyl-2′-C-methyladenosine
Catalog No. A57899
2-Chloro-N-cyclopentyl-2′-C-methyladenosine is a potent and selective agonist for A1 adenosine receptors (A1AR). This compound effectively inhibits cAMP modulation in medium spiny neurons, specifically in both direct pathway (dMSNs) and indirect pathway (iMSNs) neuronal populations. Its role as an A1AR agonist makes it valuable for research into neuropharmacology and the modulation of synaptic transmission.
Chemical Information
| Catalog Num | A57899 |
|---|---|
| M. Wt | 383.83 |
| Formula | C16H22ClN5O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 205171-12-6 |
| Synonyms | |
| SMILES | ClC1=NC2=C(C(NC3CCCC3)=N1)N=CN2[C@H]4[C@@](O)(C)[C@H](O)[C@@H](CO)O4 |
Biological Activity
| Description | 2-Chloro-N-cyclopentyl-2′-C-methyladenosine is a potent and selective agonist for A1 adenosine receptors (A1AR). This compound effectively inhibits cAMP modulation in medium spiny neurons, specifically in both direct pathway (dMSNs) and indirect pathway (iMSNs) neuronal populations. Its role as an A1AR agonist makes it valuable for research into neuropharmacology and the modulation of synaptic transmission. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
