Product Data Sheet
Evodenoson
Catalog No. A57901
Evodenoson is a selective agonist of the A2A adenosine receptor, known for its potent anti-inflammatory properties. It demonstrates significant efficacy in mitigating inflammatory responses, decreasing intestinal fluid secretion, and reducing tissue damage and neutrophil infiltration in models of Clostridium difficile toxin A exposure. Evodenoson's protective effects are attributed to its ability to inhibit myeloperoxidase (MPO) and adenosine deaminase (ADA) activities, as well as to decrease the production of tumor necrosis factor-alpha (TNF-α). This compound has valuable applications in studying inflammation-related disorders and potential therapeutic interventions.
Chemical Information
| Catalog Num | A57901 |
|---|---|
| M. Wt | 499.52 |
| Formula | C23H29N7O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 844873-47-8 |
| Synonyms | ATL 313; DE 112 |
| SMILES | O[C@H]1[C@@H](O[C@@H]([C@H]1O)C(NC2CC2)=O)N3C4=NC(C#CCC5CCN(CC5)C(OC)=O)=NC(N)=C4N=C3 |
Biological Activity
| Description | Evodenoson is a selective agonist of the A2A adenosine receptor, known for its potent anti-inflammatory properties. It demonstrates significant efficacy in mitigating inflammatory responses, decreasing intestinal fluid secretion, and reducing tissue damage and neutrophil infiltration in models of Clostridium difficile toxin A exposure. Evodenoson's protective effects are attributed to its ability to inhibit myeloperoxidase (MPO) and adenosine deaminase (ADA) activities, as well as to decrease the production of tumor necrosis factor-alpha (TNF-α). This compound has valuable applications in studying inflammation-related disorders and potential therapeutic interventions. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
