Cirazoline hydrochloride
Catalog No. A57903

Cirazoline hydrochloride is a potent full agonist of the α1A-adrenergic receptor, exhibiting a competitive inhibition constant (Ki) of 120 nM. It also acts as a partial agonist at the α1B-adrenergic receptor with a Ki of 960 nM and the α1D-adrenergic receptor with a Ki of 660 nM. This compound is valuable for research applications involving α1-adrenergic signaling pathways and the study of cardiovascular and neurological conditions.
Chemical Information
| Catalog Num | A57903 |
|---|---|
| M. Wt | 252.74 |
| Formula | C13H17ClN2O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 40600-13-3 |
| Synonyms | LD 3098 hydrochloride |
| SMILES | [H]Cl.C1(COC2=CC=CC=C2C3CC3)=NCCN1 |
Biological Activity
| Description | Cirazoline hydrochloride is a potent full agonist of the α1A-adrenergic receptor, exhibiting a competitive inhibition constant (Ki) of 120 nM. It also acts as a partial agonist at the α1B-adrenergic receptor with a Ki of 960 nM and the α1D-adrenergic receptor with a Ki of 660 nM. This compound is valuable for research applications involving α1-adrenergic signaling pathways and the study of cardiovascular and neurological conditions. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


