Product Data Sheet
DMPX
Catalog No. A57935
DMPX (3,7-Dimethyl-1-propargylxanthine) serves as a selective antagonist of the A2A adenosine receptor, demonstrating a Ki of 11 μM for the rat A2 adenosine receptor and 45 μM for the rat A1 adenosine receptor. This compound effectively crosses the blood-brain barrier and protects dopaminergic and GABAergic neurons from mitochondrial dysfunction by inhibiting A2A receptor activity in specific brain regions. DMPX is pertinent for research into neurodegenerative disorders such as depression, Parkinson's disease, and Huntington's disease.
Chemical Information
| Catalog Num | A57935 |
|---|---|
| M. Wt | 218.21 |
| Formula | C10H10N4O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 14114-46-6 |
| Synonyms | 3,7-Dimethyl-1-propargylxanthine |
| SMILES | O=C1C2=C(N(C)C(N1CC#C)=O)N=CN2C |
Biological Activity
| Description | DMPX (3,7-Dimethyl-1-propargylxanthine) serves as a selective antagonist of the A2A adenosine receptor, demonstrating a Ki of 11 μM for the rat A2 adenosine receptor and 45 μM for the rat A1 adenosine receptor. This compound effectively crosses the blood-brain barrier and protects dopaminergic and GABAergic neurons from mitochondrial dysfunction by inhibiting A2A receptor activity in specific brain regions. DMPX is pertinent for research into neurodegenerative disorders such as depression, Parkinson's disease, and Huntington's disease. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
