Product Data Sheet
Taminadenant mesylate
Catalog No. A57960
Taminadenant mesylate is a potent antagonist of the adenosine A2A receptor, exhibiting significant anti-tumor properties. It selectively binds to A2A receptors on T lymphocytes, thereby alleviating adenosine/A2A-mediated inhibition and promoting T cell-mediated immune responses against cancer cells. Additionally, Taminadenant mesylate has demonstrated efficacy in reducing hyperactivity in Parkinson's disease models by inhibiting L-DOPA-induced dyskinesias, making it a valuable reagent for research in both oncology and neuropharmacology.
Chemical Information
| Catalog Num | A57960 |
|---|---|
| M. Wt | 402.23 |
| Formula | C11H12BrN7O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2253894-81-2 |
| Synonyms | NIR178 mesylate; PBF509 mesylate |
| SMILES | BrC(C(N1C=CC=N1)=NC(N2C=CC=N2)=N3)=C3N.O=S(O)(C)=O |
Biological Activity
| Description | Taminadenant mesylate is a potent antagonist of the adenosine A2A receptor, exhibiting significant anti-tumor properties. It selectively binds to A2A receptors on T lymphocytes, thereby alleviating adenosine/A2A-mediated inhibition and promoting T cell-mediated immune responses against cancer cells. Additionally, Taminadenant mesylate has demonstrated efficacy in reducing hyperactivity in Parkinson's disease models by inhibiting L-DOPA-induced dyskinesias, making it a valuable reagent for research in both oncology and neuropharmacology. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
