Product Data Sheet

A3AR agonist 3

Catalog No. A57965

main product photo
A3AR agonist 3 is a selective agonist of the A3 adenosine receptor (A3AR), exhibiting Ki and EC50 values of 2.27 nM and 0.20 nM for human A3 receptors and cAMP modulation, respectively. This compound is valuable for studies investigating the role of A3AR in neuroinflammation, providing insights into its potential therapeutic implications in neurodegenerative conditions. Its high potency and selectivity make it a powerful tool for research involving adenosine receptor signaling pathways.
Chemical Information
Catalog NumA57965
M. Wt318.76
FormulaC15H15ClN4O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3032474-53-3
Synonyms
SMILESO[C@H]1[C@H](N2C3=C(C4=C(C=C(N4)C)C(Cl)=N3)N=C2)[C@]5([H])[C@@]([C@H]1O)([H])C5
Biological Activity
DescriptionA3AR agonist 3 is a selective agonist of the A3 adenosine receptor (A3AR), exhibiting Ki and EC50 values of 2.27 nM and 0.20 nM for human A3 receptors and cAMP modulation, respectively. This compound is valuable for studies investigating the role of A3AR in neuroinflammation, providing insights into its potential therapeutic implications in neurodegenerative conditions. Its high potency and selectivity make it a powerful tool for research involving adenosine receptor signaling pathways.
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