Product Data Sheet
A3AR modulator 1
Catalog No. A57982
A3AR Modulator 1 is a positive allosteric modulator (PAM) of the A3 adenosine receptor (A3AR). This compound significantly enhances the Cl-IB-MECA-stimulated [35S]GTPγS binding Emax, indicating its capacity to potentiate receptor activity. It is a valuable tool for research applications involving adenosine signaling pathways and may aid in the exploration of therapeutic targets related to inflammation, cancer, and neurodegenerative diseases.
Chemical Information
| Catalog Num | A57982 |
|---|---|
| M. Wt | 484.38 |
| Formula | C23H25IN4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2991693-62-8 |
| Synonyms | |
| SMILES | CCCC(C1=NC2=C(C3=C(N=C2NC4=CC=C(C=C4)I)C=CC=C3)N1)CCC |
Biological Activity
| Description | A3AR Modulator 1 is a positive allosteric modulator (PAM) of the A3 adenosine receptor (A3AR). This compound significantly enhances the Cl-IB-MECA-stimulated [35S]GTPγS binding Emax, indicating its capacity to potentiate receptor activity. It is a valuable tool for research applications involving adenosine signaling pathways and may aid in the exploration of therapeutic targets related to inflammation, cancer, and neurodegenerative diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
