Product Data Sheet
A1AR antagonist 2
Catalog No. A57985
A1AR antagonist 2 is a potent antagonist of the A1 adenosine receptor (A1AR), exhibiting inhibitory constants (Kis) of 1.49 nM for hA1, 10.2 nM for hA2A, and 50.1 nM for hA2B. This compound is valuable for research applications focused on the modulation of adenosine signaling pathways and their effects on physiological and pathological processes. Its selective inhibition of A1AR makes it a useful tool in pharmacological studies involving cardiovascular, neurological, and metabolic research.
Chemical Information
| Catalog Num | A57985 |
|---|---|
| M. Wt | 288.30 |
| Formula | C17H12N4O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1441961-74-5 |
| Synonyms | |
| SMILES | N#CC1=C(C2=CC=CC=C2)N=C(N)N=C1C3=CC=CC(O)=C3 |
Biological Activity
| Description | A1AR antagonist 2 is a potent antagonist of the A1 adenosine receptor (A1AR), exhibiting inhibitory constants (Kis) of 1.49 nM for hA1, 10.2 nM for hA2A, and 50.1 nM for hA2B. This compound is valuable for research applications focused on the modulation of adenosine signaling pathways and their effects on physiological and pathological processes. Its selective inhibition of A1AR makes it a useful tool in pharmacological studies involving cardiovascular, neurological, and metabolic research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
