Product Data Sheet
MRS5663
Catalog No. A57994
MRS5663 is a potent A3 adenosine receptor (A3AR) agonist, demonstrating an EC50 of 5.62 nM in β-arrestin2 recruitment assays. This compound exhibits significant cytoprotective effects, particularly in models of skeletal muscle ischemia-reperfusion injury and claudication. Its unique mechanism and biological activity make it a valuable tool for research in cardiovascular and metabolic disorders.
Chemical Information
| Catalog Num | A57994 |
|---|---|
| M. Wt | 452.89 |
| Formula | C22H21ClN6O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1377272-66-6 |
| Synonyms | |
| SMILES | CNC1=NC(C#CC2=CC=CC=C2Cl)=NC3=C1N=CN3[C@@H]4[C@@H](C5)[C@]5(C(NC)=O)[C@@H](O)[C@H]4O |
Biological Activity
| Description | MRS5663 is a potent A3 adenosine receptor (A3AR) agonist, demonstrating an EC50 of 5.62 nM in β-arrestin2 recruitment assays. This compound exhibits significant cytoprotective effects, particularly in models of skeletal muscle ischemia-reperfusion injury and claudication. Its unique mechanism and biological activity make it a valuable tool for research in cardiovascular and metabolic disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
