Product Data Sheet
Sch412348
Catalog No. A58066
Sch412348 is a highly potent competitive antagonist of the human adenosine A2A receptor, exhibiting a Ki value of 0.6 nM and demonstrating over 1000-fold selectivity against other adenosine receptor subtypes. This selectivity makes Sch412348 a valuable tool for studying adenosine signaling pathways. It is particularly relevant in research focusing on neurological disorders, cardiovascular conditions, and cancer, where modulation of adenosine receptors may provide therapeutic insights.
Chemical Information
| Catalog Num | A58066 |
|---|---|
| M. Wt | 465.46 |
| Formula | C22H21F2N9O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 377727-26-9 |
| Synonyms | |
| SMILES | NC1=NC(N(CCN2CCN(C3=CC=C(F)C=C3F)CC2)N=C4)=C4C5=NC(C6=CC=CO6)=NN15 |
Biological Activity
| Description | Sch412348 is a highly potent competitive antagonist of the human adenosine A2A receptor, exhibiting a Ki value of 0.6 nM and demonstrating over 1000-fold selectivity against other adenosine receptor subtypes. This selectivity makes Sch412348 a valuable tool for studying adenosine signaling pathways. It is particularly relevant in research focusing on neurological disorders, cardiovascular conditions, and cancer, where modulation of adenosine receptors may provide therapeutic insights. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
