Product Data Sheet

Pronethalol

Catalog No. A58138

main product photo
Pronethalol is a non-selective β-adrenergic antagonist that effectively inhibits β-adrenergic receptor activity. It has been shown to potently inhibit Sox2 expression and demonstrates protective effects against digitalis-induced ventricular arrhythmias. Additionally, Pronethalol limits the formation of cerebral arteriovenous malformations (AVMs), making it a valuable reagent for research into cardiovascular and neurological conditions.
Chemical Information
Catalog NumA58138
M. Wt229.32
FormulaC15H19NO
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.54-80-8
Synonyms(±)-Pronethalo
SMILESOC(CNC(C)C)C1=CC=C2C=CC=CC2=C1
Biological Activity
DescriptionPronethalol is a non-selective β-adrenergic antagonist that effectively inhibits β-adrenergic receptor activity. It has been shown to potently inhibit Sox2 expression and demonstrates protective effects against digitalis-induced ventricular arrhythmias. Additionally, Pronethalol limits the formation of cerebral arteriovenous malformations (AVMs), making it a valuable reagent for research into cardiovascular and neurological conditions.
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