Product Data Sheet
LY377604
Catalog No. A58192
LY377604 is a selective agonist of the human β3-adrenergic receptor, exhibiting an EC50 of 2.4 nM. In addition to its agonistic activity, it antagonizes β1- and β2-adrenergic receptors. This compound is utilized in research applications related to metabolic regulation, cardiovascular studies, and the exploration of therapeutic strategies for obesity and diabetes.
Chemical Information
| Catalog Num | A58192 |
|---|---|
| M. Wt | 524.61 |
| Formula | C31H32N4O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 204592-94-9 |
| Synonyms | |
| SMILES | O=C(C1=CC=C(OC2=CC=C(CC(C)(NC[C@H](O)COC3=CC=CC(N4)=C3C5=C4C=CC=C5)C)C=C2)N=C1)N |
Biological Activity
| Description | LY377604 is a selective agonist of the human β3-adrenergic receptor, exhibiting an EC50 of 2.4 nM. In addition to its agonistic activity, it antagonizes β1- and β2-adrenergic receptors. This compound is utilized in research applications related to metabolic regulation, cardiovascular studies, and the exploration of therapeutic strategies for obesity and diabetes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
