Product Data Sheet
4-Hydroxypropranolol hydrochloride
Catalog No. A58216
4-Hydroxypropranolol hydrochloride is an active metabolite of Propranolol, functioning primarily as a β1 and β2 adrenergic receptor antagonist. This compound exhibits comparable potency to its parent drug, inhibiting β1-adrenergic receptors with a pA2 value of 8.24 and β2-adrenergic receptors with a pA2 value of 8.26. Additionally, 4-Hydroxypropranolol hydrochloride possesses intrinsic sympathomimetic activity, membrane stabilizing properties, and significant antioxidant effects, making it valuable in research related to cardiovascular diseases and stress response mechanisms.
Chemical Information
| Catalog Num | A58216 |
|---|---|
| M. Wt | 311.80 |
| Formula | C16H22ClNO3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 14133-90-5 |
| Synonyms | (±)-4-hydroxy Propranolol hydrochloride |
| SMILES | OC1=C2C=CC=CC2=C(OCC(O)CNC(C)C)C=C1.Cl[H] |
Biological Activity
| Description | 4-Hydroxypropranolol hydrochloride is an active metabolite of Propranolol, functioning primarily as a β1 and β2 adrenergic receptor antagonist. This compound exhibits comparable potency to its parent drug, inhibiting β1-adrenergic receptors with a pA2 value of 8.24 and β2-adrenergic receptors with a pA2 value of 8.26. Additionally, 4-Hydroxypropranolol hydrochloride possesses intrinsic sympathomimetic activity, membrane stabilizing properties, and significant antioxidant effects, making it valuable in research related to cardiovascular diseases and stress response mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
