Product Data Sheet

(S)-Terazosin

Catalog No. A58228

main product photo
(S)-Terazosin is a selective α-adrenergic receptor antagonist, exhibiting high affinity for α1a, α1b, and α1d-adrenoceptors with Ki values of 3.91 nM, 0.79 nM, and 1.16 nM, respectively. Additionally, it interacts with α2a, α2B, and α2c-adrenoceptors, showing Ki values of 729 nM, 3.5 nM, and 46.4 nM. This compound is primarily utilized in research focused on cardiovascular conditions, benign prostatic hyperplasia, and as an innovative tool in understanding adrenergic signaling pathways.
Chemical Information
Catalog NumA58228
M. Wt387.43
FormulaC19H25N5O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.109351-33-9
Synonyms
SMILESO=C(N1CCN(C2=NC(N)=C3C=C(OC)C(OC)=CC3=N2)CC1)[C@H]4OCCC4
Biological Activity
Description(S)-Terazosin is a selective α-adrenergic receptor antagonist, exhibiting high affinity for α1a, α1b, and α1d-adrenoceptors with Ki values of 3.91 nM, 0.79 nM, and 1.16 nM, respectively. Additionally, it interacts with α2a, α2B, and α2c-adrenoceptors, showing Ki values of 729 nM, 3.5 nM, and 46.4 nM. This compound is primarily utilized in research focused on cardiovascular conditions, benign prostatic hyperplasia, and as an innovative tool in understanding adrenergic signaling pathways.
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