Product Data Sheet
α2A-AR agonist 1
Catalog No. A58289
α2A-AR agonist 1 is a selective agonist that targets the α2-adrenergic receptor (α2A-AR) with an EC50 of 0.23 nM. This compound demonstrates a significant hypnotic effect, as evidenced by an ED50 of 0.138 mg/kg in loss of righting reflex (LORR) studies. Notably, α2A-AR agonist 1 also shows metabolic stability in mouse liver microsomes, making it a valuable tool for research in pharmacology and neurobiology.
Chemical Information
| Catalog Num | A58289 |
|---|---|
| M. Wt | 279.13 |
| Formula | C12H11BrN2O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2971825-58-6 |
| Synonyms | |
| SMILES | BrC1=C(C2=CC=C1)OCCC2C3=CNC=N3 |
Biological Activity
| Description | α2A-AR agonist 1 is a selective agonist that targets the α2-adrenergic receptor (α2A-AR) with an EC50 of 0.23 nM. This compound demonstrates a significant hypnotic effect, as evidenced by an ED50 of 0.138 mg/kg in loss of righting reflex (LORR) studies. Notably, α2A-AR agonist 1 also shows metabolic stability in mouse liver microsomes, making it a valuable tool for research in pharmacology and neurobiology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
