Product Data Sheet

Nafetolol

Catalog No. A58309

main product photo
Nafetolol is a selective β1-adrenergic antagonist that effectively targets cardiac β1-adrenoceptors. This orally active β-blocking agent is utilized in research related to cardiovascular physiology and pharmacology, particularly in studies involving heart rate modulation and blood pressure regulation. With a reported half-life of approximately 2 hours in canine models, Nafetolol serves as a valuable tool for investigating β-adrenergic receptor dynamics and therapeutic interventions in cardiac conditions.
Chemical Information
Catalog NumA58309
M. Wt319.44
FormulaC19H29NO3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.42050-23-7
SynonymsK 5407 free base
SMILESOC(CNC(C)(C)C)COC(C=C1)=C(C2CCC3CC2)C3=C1O
Biological Activity
DescriptionNafetolol is a selective β1-adrenergic antagonist that effectively targets cardiac β1-adrenoceptors. This orally active β-blocking agent is utilized in research related to cardiovascular physiology and pharmacology, particularly in studies involving heart rate modulation and blood pressure regulation. With a reported half-life of approximately 2 hours in canine models, Nafetolol serves as a valuable tool for investigating β-adrenergic receptor dynamics and therapeutic interventions in cardiac conditions.
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