Product Data Sheet
CHF-6366
Catalog No. A58316
CHF-6366 is a potent M3 muscarinic antagonist and β2-adrenergic receptor agonist, exhibiting pKi values of 10.4 and 11.4, respectively. Additionally, it serves as a weak calcium channel inhibitor with an IC50 of approximately 50 μM. CHF-6366 effectively inhibits bronchoconstriction in guinea pig models, making it a valuable tool for research into chronic obstructive pulmonary disease (COPD) and related respiratory conditions.
Chemical Information
| Catalog Num | A58316 |
|---|---|
| M. Wt | 764.87 |
| Formula | C42H48N6O8 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1615208-41-7 |
| Synonyms | |
| SMILES | O=C(C1=NN(C)C(COC2=CC=CC([C@H](C3=CC=CC=C3)NC(O[C@H]4CN5CCC4CC5)=O)=C2)=C1)OCCCCNC[C@H](O)C6=CC=C(O)C7=C6C=CC(N7)=O |
Biological Activity
| Description | CHF-6366 is a potent M3 muscarinic antagonist and β2-adrenergic receptor agonist, exhibiting pKi values of 10.4 and 11.4, respectively. Additionally, it serves as a weak calcium channel inhibitor with an IC50 of approximately 50 μM. CHF-6366 effectively inhibits bronchoconstriction in guinea pig models, making it a valuable tool for research into chronic obstructive pulmonary disease (COPD) and related respiratory conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
