Product Data Sheet
Nomifensine-d3 maleate
Catalog No. A58331
Nomifensine-d3 maleate is a deuterium-labeled derivative of Nomifensine maleate, a potent inhibitor of norepinephrine (NE) and dopamine (DA) reuptake. It effectively blocks the reuptake of NE, DA, and serotonin (5-HT) in rat brain synaptosomes, with IC50 values of 6.6 nM, 48 nM, and 830 nM, respectively. This compound displays antidepressant and analgesic properties, and is applicable in research related to neurodegenerative diseases, substance addiction, and pain mechanisms.
Chemical Information
| Catalog Num | A58331 |
|---|---|
| M. Wt | 357.42 |
| Formula | C20H19D3N2O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1795140-41-8 |
| Synonyms | (±)-Nomifensine-d3 maleate; Nomifensin-d3 maleate |
| SMILES | OC(/C=C/C(O)=O)=O.NC1=C2C(C(C3=CC=CC=C3)CN(C2)C([2H])([2H])[2H])=CC=C1 |
Biological Activity
| Description | Nomifensine-d3 maleate is a deuterium-labeled derivative of Nomifensine maleate, a potent inhibitor of norepinephrine (NE) and dopamine (DA) reuptake. It effectively blocks the reuptake of NE, DA, and serotonin (5-HT) in rat brain synaptosomes, with IC50 values of 6.6 nM, 48 nM, and 830 nM, respectively. This compound displays antidepressant and analgesic properties, and is applicable in research related to neurodegenerative diseases, substance addiction, and pain mechanisms. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
