Product Data Sheet
Cyclazosin hydrochloride
Catalog No. A58415
Cyclazosin hydrochloride is an α1B-adrenergic receptor antagonist that exhibits high specificity for α-adrenergic receptors, with reported pKi values ranging from 9.23 to 9.57 for O/1A and 8.18 to 8.41 for OflB receptors. This compound is utilized in research to study the role of α-adrenergic signaling in various physiological processes and to explore potential therapeutic applications in conditions influenced by adrenergic activity. However, Cyclazosin hydrochloride does not differentiate between cloned alb and alo adrenergic receptor subtypes, exhibiting similar affinity profiles.
Chemical Information
| Catalog Num | A58415 |
|---|---|
| M. Wt | 473.95 |
| Formula | C23H28ClN5O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 146929-33-1 |
| Synonyms | |
| SMILES | COC1=CC2=NC(N3CCN(C(C4=CC=CO4)=O)[C@@]5([H])CCCC[C@@]35[H])=NC(N)=C2C=C1OC.Cl |
Biological Activity
| Description | Cyclazosin hydrochloride is an α1B-adrenergic receptor antagonist that exhibits high specificity for α-adrenergic receptors, with reported pKi values ranging from 9.23 to 9.57 for O/1A and 8.18 to 8.41 for OflB receptors. This compound is utilized in research to study the role of α-adrenergic signaling in various physiological processes and to explore potential therapeutic applications in conditions influenced by adrenergic activity. However, Cyclazosin hydrochloride does not differentiate between cloned alb and alo adrenergic receptor subtypes, exhibiting similar affinity profiles. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
