Product Data Sheet
4-Hydroxypropranolol-d7
Catalog No. A58443
4-Hydroxypropranolol-d7 is a deuterium-labeled derivative of the active metabolite 4-Hydroxypropranolol hydrochloride, which targets β1- and β2-adrenergic receptors with high affinity, exhibiting pA2 values of 8.24 and 8.26, respectively. This compound maintains comparable potency to Propranolol and displays intrinsic sympathomimetic activity, membrane-stabilizing properties, and potent antioxidant effects. 4-Hydroxypropranolol-d7 is instrumental for pharmacokinetic studies, providing valuable insights into drug metabolism and receptor activity in various biological assays.
Chemical Information
| Catalog Num | A58443 |
|---|---|
| M. Wt | 282.39 |
| Formula | C16H14D7NO3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1219908-86-7 |
| Synonyms | (±)-4-Hydroxy Propranolol-d7 |
| SMILES | OC1=CC=C(C2=C1C=CC=C2)OCC(CNC(C([2H])([2H])[2H])(C([2H])([2H])[2H])[2H])O |
Biological Activity
| Description | 4-Hydroxypropranolol-d7 is a deuterium-labeled derivative of the active metabolite 4-Hydroxypropranolol hydrochloride, which targets β1- and β2-adrenergic receptors with high affinity, exhibiting pA2 values of 8.24 and 8.26, respectively. This compound maintains comparable potency to Propranolol and displays intrinsic sympathomimetic activity, membrane-stabilizing properties, and potent antioxidant effects. 4-Hydroxypropranolol-d7 is instrumental for pharmacokinetic studies, providing valuable insights into drug metabolism and receptor activity in various biological assays. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
