Product Data Sheet
AP-7-168
Catalog No. A58454
AP-7-168 is a β-arrestin-biased negative allosteric modulator of the β2-adrenergic receptor (β2AR). It functions by promoting β2AR homodimerization and inhibiting GRK5-mediated phosphorylation, thereby sustaining bronchorelaxation in both cell and tissue models. This compound is particularly valuable for research in inflammation and immunology, including studies related to asthma and other respiratory conditions.
Chemical Information
| Catalog Num | A58454 |
|---|---|
| M. Wt | 433.29 |
| Formula | C20H19BrF2N4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2816062-15-2 |
| Synonyms | |
| SMILES | FC1=C(C=C(C=C1)NC2=NC3=CC=C(C=C3C(NC4CCCCC4)=N2)Br)F |
Biological Activity
| Description | AP-7-168 is a β-arrestin-biased negative allosteric modulator of the β2-adrenergic receptor (β2AR). It functions by promoting β2AR homodimerization and inhibiting GRK5-mediated phosphorylation, thereby sustaining bronchorelaxation in both cell and tissue models. This compound is particularly valuable for research in inflammation and immunology, including studies related to asthma and other respiratory conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
