Product Data Sheet

(+)-Amosulalol (d-Amosulalol)

Catalog No. A58476

main product photo
(+)-Amosulalol is an adrenergic receptor inhibitor that serves as an orally active dual blocker of α1 and β1-adrenergic receptors. This compound demonstrates significant antihypertensive activity by selectively inhibiting α1-adrenergic receptors, while also reducing reflex tachycardia and plasma renin activity in spontaneously hypertensive rats through β1-adrenergic receptor inhibition. As a valuable research tool, (+)-Amosulalol can be employed in studies related to cardiovascular physiology and pharmacology.
Chemical Information
Catalog NumA58476
M. Wt380.46
FormulaC18H24N2O5S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.94666-17-8
Synonyms(+)-YM 09538
SMILESO=S(C1=CC([C@H](O)CNCCOC2=CC=CC=C2OC)=CC=C1C)(N)=O
Biological Activity
Description(+)-Amosulalol is an adrenergic receptor inhibitor that serves as an orally active dual blocker of α1 and β1-adrenergic receptors. This compound demonstrates significant antihypertensive activity by selectively inhibiting α1-adrenergic receptors, while also reducing reflex tachycardia and plasma renin activity in spontaneously hypertensive rats through β1-adrenergic receptor inhibition. As a valuable research tool, (+)-Amosulalol can be employed in studies related to cardiovascular physiology and pharmacology.
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