Product Data Sheet

Phendioxan

Catalog No. A58484

main product photo
Phendioxan is a selective adrenergic receptor ligand with a high binding affinity for the α(1)-adrenaline receptor subtype. Its facilitated membrane diffusion enhances its efficacy at the α(1d)-AR, supporting its potential in cardiovascular and neuropharmacological research. Docking simulations have elucidated the significant roles of polar, electrostatic, hydrophobic, and shape interactions of its phenoxy terminal substituents in ligand-receptor binding dynamics.
Chemical Information
Catalog NumA58484
M. Wt421.49
FormulaC25H27NO5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.130905-04-3
Synonyms
SMILESCOC(C=CC=C1OC)=C1OCCNC[C@H]2[C@H](C3=CC=CC=C3)OC4=CC=CC=C4O2
Biological Activity
DescriptionPhendioxan is a selective adrenergic receptor ligand with a high binding affinity for the α(1)-adrenaline receptor subtype. Its facilitated membrane diffusion enhances its efficacy at the α(1d)-AR, supporting its potential in cardiovascular and neuropharmacological research. Docking simulations have elucidated the significant roles of polar, electrostatic, hydrophobic, and shape interactions of its phenoxy terminal substituents in ligand-receptor binding dynamics.
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