Phendioxan
Catalog No. A58484

Phendioxan is a selective adrenergic receptor ligand with a high binding affinity for the α(1)-adrenaline receptor subtype. Its facilitated membrane diffusion enhances its efficacy at the α(1d)-AR, supporting its potential in cardiovascular and neuropharmacological research. Docking simulations have elucidated the significant roles of polar, electrostatic, hydrophobic, and shape interactions of its phenoxy terminal substituents in ligand-receptor binding dynamics.
Chemical Information
| Catalog Num | A58484 |
|---|---|
| M. Wt | 421.49 |
| Formula | C25H27NO5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 130905-04-3 |
| Synonyms | |
| SMILES | COC(C=CC=C1OC)=C1OCCNC[C@H]2[C@H](C3=CC=CC=C3)OC4=CC=CC=C4O2 |
Biological Activity
| Description | Phendioxan is a selective adrenergic receptor ligand with a high binding affinity for the α(1)-adrenaline receptor subtype. Its facilitated membrane diffusion enhances its efficacy at the α(1d)-AR, supporting its potential in cardiovascular and neuropharmacological research. Docking simulations have elucidated the significant roles of polar, electrostatic, hydrophobic, and shape interactions of its phenoxy terminal substituents in ligand-receptor binding dynamics. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


