Product Data Sheet

(±)-Penbutolol ((Rac)-Penbutolol)

Catalog No. A58497

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(±)-Penbutolol is a racemic mixture functioning as a β-adrenergic receptor antagonist. It is known to mitigate exercise-induced tachycardia, reduce the exercise-related increase in peak expiratory flow rate (PEFR), and lower resting plasma renin activity (PRA). With a peak plasma concentration achieved one hour after oral administration and a half-life of 4.5 hours, (±)-Penbutolol also converts into an active metabolite. This compound is valuable for research in cardiovascular diseases and related physiological studies.
Chemical Information
Catalog NumA58497
M. Wt291.43
FormulaC18H29NO2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.36507-48-9
Synonyms(Rac)-Penbutolol; (±)-Isopenbutolol
SMILESOC(CNC(C)(C)C)COC1=CC=CC=C1C2CCCC2
Biological Activity
Description(±)-Penbutolol is a racemic mixture functioning as a β-adrenergic receptor antagonist. It is known to mitigate exercise-induced tachycardia, reduce the exercise-related increase in peak expiratory flow rate (PEFR), and lower resting plasma renin activity (PRA). With a peak plasma concentration achieved one hour after oral administration and a half-life of 4.5 hours, (±)-Penbutolol also converts into an active metabolite. This compound is valuable for research in cardiovascular diseases and related physiological studies.
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