(R)-Bambuterol
Catalog No. A58576

(R)-Bambuterol is a selective β2-adrenergic receptor agonist known for its anti-asthmatic properties. This compound has demonstrated efficacy in treating asthma and chronic obstructive pulmonary disease (COPD), offering the advantage of once-daily administration with minimal side effects. In preclinical studies, (R)-Bambuterol effectively alleviated disease severity in colitis models, significantly lowering inflammatory cytokines and macrophage infiltration in affected tissues. Additionally, it upregulates β2-adrenoceptor levels and suppresses the expression of pro-inflammatory markers such as IL-6 and IL-17 in colon tissue in a dose-dependent manner, making it a valuable tool for research in inflammatory diseases.
Chemical Information
| Catalog Num | A58576 |
|---|---|
| M. Wt | 367.44 |
| Formula | C18H29N3O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 788821-30-7 |
| Synonyms | |
| SMILES | CC(C)(C)NC[C@@H](C1=CC(OC(N(C)C)=O)=CC(OC(N(C)C)=O)=C1)O |
Biological Activity
| Description | (R)-Bambuterol is a selective β2-adrenergic receptor agonist known for its anti-asthmatic properties. This compound has demonstrated efficacy in treating asthma and chronic obstructive pulmonary disease (COPD), offering the advantage of once-daily administration with minimal side effects. In preclinical studies, (R)-Bambuterol effectively alleviated disease severity in colitis models, significantly lowering inflammatory cytokines and macrophage infiltration in affected tissues. Additionally, it upregulates β2-adrenoceptor levels and suppresses the expression of pro-inflammatory markers such as IL-6 and IL-17 in colon tissue in a dose-dependent manner, making it a valuable tool for research in inflammatory diseases. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


