JNJ-7925476 hydrochloride
Catalog No. A58578

JNJ-7925476 hydrochloride is a triple monoamine uptake inhibitor that targets adrenergic receptors to modulate neurotransmitter availability. It demonstrates significant antidepressant activity, as evidenced by increased extracellular levels of serotonin, dopamine, and norepinephrine in the rat cerebral cortex. This compound is applicable in preclinical research to investigate the mechanisms underlying mood disorders and therapeutic interventions. Additionally, its rapid absorption and higher concentration in the brain support its potential for effective neurological studies.
Chemical Information
| Catalog Num | A58578 |
|---|---|
| M. Wt | 309.83 |
| Formula | C20H20ClN |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 109085-56-5 |
| Synonyms | |
| SMILES | C#CC1=CC=C(C=C1)[C@H]2C3=CC=CC=C3[C@]4([H])N(CCC4)C2.Cl |
Biological Activity
| Description | JNJ-7925476 hydrochloride is a triple monoamine uptake inhibitor that targets adrenergic receptors to modulate neurotransmitter availability. It demonstrates significant antidepressant activity, as evidenced by increased extracellular levels of serotonin, dopamine, and norepinephrine in the rat cerebral cortex. This compound is applicable in preclinical research to investigate the mechanisms underlying mood disorders and therapeutic interventions. Additionally, its rapid absorption and higher concentration in the brain support its potential for effective neurological studies. |
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RETURN POLICY
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


