Product Data Sheet
GG-818
Catalog No. A58622
GG-818 is a selective antagonist of the α1 adrenoceptor, exhibiting potent inhibition with pKi values of 9.7 for α1a, 7.8 for α1b, and 7.6 for α1d. This compound is valuable in the study of benign prostatic hyperplasia and contributes to understanding α1 adrenoceptor-mediated signaling pathways and their implications in urological health. Its specificity may facilitate research into potential therapeutic interventions targeting α1 adrenergic receptors.
Chemical Information
| Catalog Num | A58622 |
|---|---|
| M. Wt | 571.58 |
| Formula | C26H29F4N3O5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 179535-60-5 |
| Synonyms | GW 1818 |
| SMILES | O=S(C1=CC(CCN2CCC(C3=NC(COCC(F)(F)F)=C(C4=CC=C(F)C=C4)O3)CC2)=CC=C1OC)(N)=O |
Biological Activity
| Description | GG-818 is a selective antagonist of the α1 adrenoceptor, exhibiting potent inhibition with pKi values of 9.7 for α1a, 7.8 for α1b, and 7.6 for α1d. This compound is valuable in the study of benign prostatic hyperplasia and contributes to understanding α1 adrenoceptor-mediated signaling pathways and their implications in urological health. Its specificity may facilitate research into potential therapeutic interventions targeting α1 adrenergic receptors. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
