Product Data Sheet

Atenolol hydrochloride

Catalog No. A58635

main product photo
Atenolol hydrochloride is a cardioselective β1-adrenergic receptor blocker, exhibiting a Ki of 697 nM at the β1-adrenoceptor in guinea pig left ventricle membranes. This compound is primarily used in the investigation of cardiovascular conditions such as hypertension and angina pectoris, providing insights into heart rate modulation and blood pressure regulation. Its selective mechanism makes it a valuable tool for researchers studying adrenergic signaling pathways and therapeutic approaches for cardiac disorders.
Chemical Information
Catalog NumA58635
M. Wt302.80
FormulaC14H23ClN2O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.51706-40-2
Synonyms(RS)-Atenolol hydrochloride; Tenormin hydrochloride; ICI 66082 hydrochloride
SMILESO=C(N)CC1=CC=C(OCC(O)CNC(C)C)C=C1.Cl
Biological Activity
DescriptionAtenolol hydrochloride is a cardioselective β1-adrenergic receptor blocker, exhibiting a Ki of 697 nM at the β1-adrenoceptor in guinea pig left ventricle membranes. This compound is primarily used in the investigation of cardiovascular conditions such as hypertension and angina pectoris, providing insights into heart rate modulation and blood pressure regulation. Its selective mechanism makes it a valuable tool for researchers studying adrenergic signaling pathways and therapeutic approaches for cardiac disorders.
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