Product Data Sheet
UK 14819
Catalog No. A58664
UK 14819 is a potent α2-adrenoceptor agonist that selectively activates alpha-2 adrenergic receptors. This compound effectively inhibits stimulation-induced contractions in rabbit distal colon, demonstrating an IC50 value of 6.66 nM. UK 14819 is primarily used in pharmacological research to investigate the role of α2-adrenoceptors in gastrointestinal motility and related physiological processes.
Chemical Information
| Catalog Num | A58664 |
|---|---|
| M. Wt | 247.69 |
| Formula | C11H10ClN5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 91147-46-5 |
| Synonyms | 5-Desbromo, 5-chloro brimonidine |
| SMILES | ClC1=C2N=CC=NC2=CC=C1NC3=NCCN3 |
Biological Activity
| Description | UK 14819 is a potent α2-adrenoceptor agonist that selectively activates alpha-2 adrenergic receptors. This compound effectively inhibits stimulation-induced contractions in rabbit distal colon, demonstrating an IC50 value of 6.66 nM. UK 14819 is primarily used in pharmacological research to investigate the role of α2-adrenoceptors in gastrointestinal motility and related physiological processes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
