Product Data Sheet
3-MPPI
Catalog No. A58669
3-MPPI is a selective G protein-coupled receptor (GPCR) ligand with a strong affinity for the α1-adrenergic receptor, exhibiting a Ki value of 0.21 nM, while its activity on the 5-HT1A receptor is significantly lower at 50 nM. This compound effectively modulates the signaling pathways associated with the α1-adrenergic receptor. Research applications of 3-MPPI include studies on hypertension, the effects of stress-induced anxiety-like behavior, and investigations into levodopa-induced dyskinesia.
Chemical Information
| Catalog Num | A58669 |
|---|---|
| M. Wt | 419.49 |
| Formula | C23H25N5O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 133399-65-2 |
| Synonyms | |
| SMILES | O=C1NC=2C=3C=CC=CC3NC2C(=O)N1CCN4CCN(C=5C=CC=CC5OC)CC4 |
Biological Activity
| Description | 3-MPPI is a selective G protein-coupled receptor (GPCR) ligand with a strong affinity for the α1-adrenergic receptor, exhibiting a Ki value of 0.21 nM, while its activity on the 5-HT1A receptor is significantly lower at 50 nM. This compound effectively modulates the signaling pathways associated with the α1-adrenergic receptor. Research applications of 3-MPPI include studies on hypertension, the effects of stress-induced anxiety-like behavior, and investigations into levodopa-induced dyskinesia. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
