Product Data Sheet

Mabuterol hydrochloride

Catalog No. A58727

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Mabuterol hydrochloride is a selective, orally active agonist of the beta-2 adrenergic receptor (ADRB2). This compound demonstrates key biological activity by inhibiting cell proliferation and reducing intracellular calcium levels induced by PDGF-BB. Additionally, Mabuterol hydrochloride downregulates protein expression of Drp-1, cyclin D1, and PCNA, while enhancing Mfn-2 expression in response to PDGF-BB. These properties make Mabuterol hydrochloride valuable for research in cellular signaling and related therapeutic applications.
Chemical Information
Catalog NumA58727
M. Wt347.20
FormulaC13H19Cl2F3N2O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.54240-36-7
Synonyms
SMILESCC(NCC(O)C1=CC(C(F)(F)F)=C(N)C(Cl)=C1)(C)C.[H]Cl
Biological Activity
DescriptionMabuterol hydrochloride is a selective, orally active agonist of the beta-2 adrenergic receptor (ADRB2). This compound demonstrates key biological activity by inhibiting cell proliferation and reducing intracellular calcium levels induced by PDGF-BB. Additionally, Mabuterol hydrochloride downregulates protein expression of Drp-1, cyclin D1, and PCNA, while enhancing Mfn-2 expression in response to PDGF-BB. These properties make Mabuterol hydrochloride valuable for research in cellular signaling and related therapeutic applications.
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SHIPPING AND STORAGE
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