Product Data Sheet
5,6-Epoxyeicosatrienoic acid-d11
Catalog No. A58736
5,6-Epoxyeicosatrienoic acid-d11 is a deuterium-labeled analogue of 5,6-Epoxyeicosatrienoic acid (5,6-EET), a compound synthesized from arachidonic acid by cytochrome P450 enzymes. This stable isotope is valuable for studying the biological activities of 5,6-EET, which include modulation of calcium mobilization and hormone secretion in neuroendocrine cells, as well as inhibition of T-type voltage-gated calcium channels (Cav3.1, Cav3.2). Additionally, it functions as a substrate for COX-1 and COX-2, facilitating detailed metabolic studies. 5,6-Epoxyeicosatrienoic acid-d11 aids in quantification and mechanistic investigations through methods such as GC-MS.
Chemical Information
| Catalog Num | A58736 |
|---|---|
| M. Wt | 331.53 |
| Formula | C20H21D11O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1881277-30-0 |
| Synonyms | 5,6-EET-d11; (±)5,6-EpETrE-d11 |
| SMILES | [2H]C([2H])(C([2H])(C([2H])(/C=C\C/C=C\C/C=C\C[C@H]1O[C@H]1CCCC(O)=O)[2H])[2H])C([2H])(C([2H])([2H])[2H])[2H] |
Biological Activity
| Description | 5,6-Epoxyeicosatrienoic acid-d11 is a deuterium-labeled analogue of 5,6-Epoxyeicosatrienoic acid (5,6-EET), a compound synthesized from arachidonic acid by cytochrome P450 enzymes. This stable isotope is valuable for studying the biological activities of 5,6-EET, which include modulation of calcium mobilization and hormone secretion in neuroendocrine cells, as well as inhibition of T-type voltage-gated calcium channels (Cav3.1, Cav3.2). Additionally, it functions as a substrate for COX-1 and COX-2, facilitating detailed metabolic studies. 5,6-Epoxyeicosatrienoic acid-d11 aids in quantification and mechanistic investigations through methods such as GC-MS. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
