Product Data Sheet
Fipamezole hydrochloride
Catalog No. A58796
Fipamezole hydrochloride is a potent α2-adrenergic receptor antagonist, exhibiting Ki values of 9.2 nM, 17 nM, and 55 nM for human α2A, α2B, and α2C receptors, respectively. This compound functions as an anti-dyskinetic agent, making it valuable for research into Parkinson's disease. Its selective action on α2-adrenergic receptors offers insights into the modulation of dopaminergic activity and potential therapeutic strategies for movement disorders.
Chemical Information
| Catalog Num | A58796 |
|---|---|
| M. Wt | 266.74 |
| Formula | C14H16ClFN2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 150586-72-4 |
| Synonyms | MPV-1730 hydrochloride; JP-1730 hydrochloride |
| SMILES | FC1=CC2=C(CC(C3=CN=CN3)(CC)C2)C=C1.Cl |
Biological Activity
| Description | Fipamezole hydrochloride is a potent α2-adrenergic receptor antagonist, exhibiting Ki values of 9.2 nM, 17 nM, and 55 nM for human α2A, α2B, and α2C receptors, respectively. This compound functions as an anti-dyskinetic agent, making it valuable for research into Parkinson's disease. Its selective action on α2-adrenergic receptors offers insights into the modulation of dopaminergic activity and potential therapeutic strategies for movement disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
