Product Data Sheet
Angiotensin II (5-8), human
Catalog No. A58907
Angiotensin II (5-8), human is a biologically active C-terminal fragment of the vasoconstrictor angiotensin II, targeting the angiotensin II type 1 (AT1) receptor. This fragment activates G protein-coupled receptors (GPCRs) in vascular smooth muscle cells, leading to increased intracellular calcium levels and vasoconstriction. Additionally, Angiotensin II (5-8) influences renal function by interacting with the Na+/H+ exchanger in the proximal tubules, making it a valuable tool for research in cardiovascular and renal physiology.
Chemical Information
| Catalog Num | A58907 |
|---|---|
| M. Wt | 512.60 |
| Formula | C26H36N6O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 34233-50-6 |
| Synonyms | |
| SMILES | CC[C@H](C)[C@H](N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O |
Biological Activity
| Description | Angiotensin II (5-8), human is a biologically active C-terminal fragment of the vasoconstrictor angiotensin II, targeting the angiotensin II type 1 (AT1) receptor. This fragment activates G protein-coupled receptors (GPCRs) in vascular smooth muscle cells, leading to increased intracellular calcium levels and vasoconstriction. Additionally, Angiotensin II (5-8) influences renal function by interacting with the Na+/H+ exchanger in the proximal tubules, making it a valuable tool for research in cardiovascular and renal physiology. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
