Product Data Sheet
Losartan-d3 Carboxylic Acid
Catalog No. A58943
Losartan-d3 Carboxylic Acid is a deuterium-labeled derivative of Losartan, which serves as an angiotensin II receptor antagonist. It inhibits the binding of angiotensin II to AT1 receptors with an IC50 of 20 nM, making it valuable in cardiovascular research. This stable isotope is particularly useful for pharmacokinetic studies, enabling accurate tracking and quantification of Losartan in biological systems.
Chemical Information
| Catalog Num | A58943 |
|---|---|
| M. Wt | 439.91 |
| Formula | C22H18D3ClN6O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1189729-40-5 |
| Synonyms | |
| SMILES | [2H]C([2H])([2H])CCCC1=NC(Cl)=C(C(O)=O)N1CC2=CC=C(C3=C(C4=NN=NN4)C=CC=C3)C=C2 |
Biological Activity
| Description | Losartan-d3 Carboxylic Acid is a deuterium-labeled derivative of Losartan, which serves as an angiotensin II receptor antagonist. It inhibits the binding of angiotensin II to AT1 receptors with an IC50 of 20 nM, making it valuable in cardiovascular research. This stable isotope is particularly useful for pharmacokinetic studies, enabling accurate tracking and quantification of Losartan in biological systems. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
