Product Data Sheet
ZD 7155
Catalog No. A58952
ZD 7155 is a selective antagonist of the angiotensin II type 1 receptor (AT1R), known for its effects on renal function. Research indicates that ZD 7155 modulates electrolyte excretion, particularly increasing the excretion of sodium, potassium, and chloride in postnatal lamb models. In studies involving 6-week-old lambs, pretreatment with ZD 7155 significantly enhanced urine flow rates and free water clearance, while also reducing urine osmolality. This compound is essential for investigating the role of AT1R in renal physiology and the interactions with nitric oxide in electrolyte regulation.
Chemical Information
| Catalog Num | A58952 |
|---|---|
| M. Wt | 438.52 |
| Formula | C26H26N6O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 151801-76-2 |
| Synonyms | |
| SMILES | O=C1CCC2=C(C=C(CC)N=C2CC)N1CC(C=C3)=CC=C3C4=CC=CC=C4C5=NN=NN5 |
Biological Activity
| Description | ZD 7155 is a selective antagonist of the angiotensin II type 1 receptor (AT1R), known for its effects on renal function. Research indicates that ZD 7155 modulates electrolyte excretion, particularly increasing the excretion of sodium, potassium, and chloride in postnatal lamb models. In studies involving 6-week-old lambs, pretreatment with ZD 7155 significantly enhanced urine flow rates and free water clearance, while also reducing urine osmolality. This compound is essential for investigating the role of AT1R in renal physiology and the interactions with nitric oxide in electrolyte regulation. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
