Product Data Sheet
Angiotensin II (1-4), human
Catalog No. A58979
Angiotensin II (1-4), human is an endogenous peptide that functions as an agonist for the angiotensin receptor. It primarily binds to the AT II type 1 (AT1) receptor, activating GPCRs in vascular smooth muscle cells, which leads to an increase in intracellular calcium levels. Additionally, Angiotensin II (1-4) influences the sodium/hydrogen exchanger in the proximal tubules of the kidney, playing a critical role in regulating blood pressure and fluid balance. This peptide is valuable for research applications related to cardiovascular function and renal physiology.
Chemical Information
| Catalog Num | A58979 |
|---|---|
| M. Wt | 551.59 |
| Formula | C24H37N7O8 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 52580-29-7 |
| Synonyms | |
| SMILES | [C@H](C(N[C@H](C(N[C@@H](CC1=CC=C(O)C=C1)C(O)=O)=O)C(C)C)=O)(NC([C@H](CC(O)=O)N)=O)CCCNC(=N)N |
Biological Activity
| Description | Angiotensin II (1-4), human is an endogenous peptide that functions as an agonist for the angiotensin receptor. It primarily binds to the AT II type 1 (AT1) receptor, activating GPCRs in vascular smooth muscle cells, which leads to an increase in intracellular calcium levels. Additionally, Angiotensin II (1-4) influences the sodium/hydrogen exchanger in the proximal tubules of the kidney, playing a critical role in regulating blood pressure and fluid balance. This peptide is valuable for research applications related to cardiovascular function and renal physiology. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
