Product Data Sheet
Monlunabant
Catalog No. A59077
Monlunabant is a selective antagonist of the cannabinoid receptor 1 (CB1) with an inhibitory constant (Ki) of 0.3 nM for human CB1 receptors, and 613 nM for human CB2 receptors. This compound demonstrates potent activity in modulating cannabinoid signaling pathways, making it a valuable tool for researching the roles of CB1 in various physiological processes. Its applications include the exploration of metabolic disorders, neurodegenerative diseases, and potential therapeutic interventions involving the endocannabinoid system.
Chemical Information
| Catalog Num | A59077 |
|---|---|
| M. Wt | 591.00 |
| Formula | C26H22ClF3N6O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2712480-46-9 |
| Synonyms | (S)-MRI-1891; INV-202 |
| SMILES | O=S(N/C(N1N=C(C2=CC=C(C=C2)Cl)[C@@H](C3=CC=CC=C3)C1)=N/C(NC(C)=O)=N)(C4=CC=C(C=C4)C(F)(F)F)=O |
Biological Activity
| Description | Monlunabant is a selective antagonist of the cannabinoid receptor 1 (CB1) with an inhibitory constant (Ki) of 0.3 nM for human CB1 receptors, and 613 nM for human CB2 receptors. This compound demonstrates potent activity in modulating cannabinoid signaling pathways, making it a valuable tool for researching the roles of CB1 in various physiological processes. Its applications include the exploration of metabolic disorders, neurodegenerative diseases, and potential therapeutic interventions involving the endocannabinoid system. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
